CHEMBL3586418


SMILES O=C(c1ccccc1-c1ccccc1)N1C[C@H]2CN(c3nc4ccccc4s3)C[C@H]2C1
InChIKey KMRQOILICWFMTR-BGYRXZFFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.85 5.85 5.85 ChEMBL
OX2 OX2R Human Orexin A pKi 6.16 6.16 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database