CHEMBL3260337


SMILES C[C@@H](Oc1ccc(C(F)(F)F)cc1OC1CNC1)c1cccc(C(F)(F)F)c1
InChIKey PQHWHHSAKLPIFS-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 405.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.12 5.12 5.12 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database