CHEMBL3220215


SMILES Cc1nc2c(o1)CC(CN1CCC(c3c[nH]c4cc(F)ccc34)CC1)CC2=O
InChIKey RXIUGRLQOGTTNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.87 5.87 5.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database