Structure information

M2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4MQT

SPECIES

Homo sapiens

RESOLUTION

3.700

PREFERRED CHAIN

A

PUBLICATION DATE

Nov. 27, 2013

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
2CU Y80 2.61x60 TM2 polar (hydrogen bond)
2CU Y83 2.64x63 TM2 hydrophobic
Iperoxo Y104 3.33x33 TM3 hydrophobic
2CU Y177 45.51x51 ECL2 aromatic (face-to-face)
Iperoxo A194 5.46x461 TM5 hydrophobic
Iperoxo W400 6.48x48 TM6 hydrophobic
Iperoxo N404 6.52x52 TM6 polar (hydrogen bond)
2CU N410 6.58x58 TM6 polar (hydrogen bond)
2CU N419 7.32x31 TM7 polar (hydrogen bond)
2CU W422 7.35x34 TM7 aromatic (face-to-face)

Ligands

2CU

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Iperoxo

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N G I I T V L S L S G A V L V I F V V 1 F S L A C A D L I I G F V S M N L Y T L Y 2 I L L N M V S A N S V V Y D L A L W L D 3 A G M M I A A A W V L S F I L W A P A I 4 Y L V T M I I V P L Y F A A I A T G F T V 5 L A I L L A F I I T W A P Y N V M V L I 6 A P N I T S N I Y C L W Y G I T W V T 7
Download: PNG | SVG
ICL1 R H L Q ICL1ECL1 Y W P L ECL1ICL2 P L T Y P V K R ICL2ECL2 V R T V E D G E C Y I Q F F S ECL2ICL3 P V A N Q D P V S P S L V Q G R I V K P N N N N M P S S D D G L E H N K I Q N G K A P R D P V T E N C V Q G E E K E S S N D S T S V S A V A S N M R D D E I T Q D E N T V S T S L G H S K D E N S K Q T C I R I G T K T P K S D S C T P T N T T V E V V G S S G Q N G D E K Q N I V A R K I V K M T K Q P A K K ICL3ECL3 A P C I ECL3N-term M N N S T N S S N N S L A L T S P Y N-termC-term C H Y K N I G A T R C-term K T F E V V F I V L V A G S L S L V T I I G N I L V M V S I K V N T V N N Y F L F S L A C A D L I I G V F S M N L Y T L Y T V I G G P V V C D L W L A L D Y V V S N A S V M N L L I I S F D R Y F C V T K T T K M A G M M I A A A W V L S F I L W A P A I L F W Q F I V G N A A V T F G T A I A A F Y L P V I I M T V L Y W H I S R A S K S R I K K D K K E K P P P S R E K K V T R T I L A I L L A F I I T W A P Y N V M V L I N T F C P N T V W T I G Y W L C Y I N S T I N P A C Y A L C N A T F K H F K K T L L M
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
M2 receptor
TM2
2x60 2.61x60 Y80
2x63 2.64x63 Y83
TM3
3x33 3.33x33 Y104
ECL2
45x51 45.51x51 Y177
TM5
5x461 5.46x461 A194
TM6
6x48 6.48x48 W400
6x52 6.52x52 N404
6x58 6.58x58 N410
TM7
7x31 7.32x31 N419
7x34 7.35x34 W422