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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
acm1_human 181 ECL2 Q => A 7.246↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 2.3↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1994)
acm1_human 5.35x36 185 TM5 Q => A 1.318↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 117.49↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 183 ECL2 L => A 3.631↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 2.512↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 7.586↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.441↑ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.388↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.175↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 28.9↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 4.571↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.089↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.82↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 2.561↓ IC50 (Binding - Radioligand competition/displacement) Pirenzepine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 11.111↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.52x52 417 TM7 C => S N/A N/A Lucas JL et al (2001)
acm1_human 2.61x60 82 TM2 Y => F 1.35↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.089↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 394 ECL3 C => A 2.137↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F N/A N/A Matsui H et al (1995)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.235↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 29.512↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.24x24 354 TM6 T => A N/A N/A Lameh J et al (1992)
acm1_human 3.28x28 101 TM3 W => F 1.38↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 3.631↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 4.66x66 166 TM4 Y => A 2.455↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.122↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.52x52 125 TM3 F => A N/A N/A Moro O et al (1994)
acm1_human 3.33x33 106 TM3 Y => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 18.197↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 5.128↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 42.308↓ K(i) (Binding - Radioligand competition/displacement) Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.64x64 214 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 7.35x34 400 TM7 W => A 9.12↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 9.12↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.739↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.175↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.722↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 2.138↓ pK(A) (Binding - Radioligand competition/displacement) 77-LH-28-1 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 128.825↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => M N/A N/A Moro O et al (1993)
acm1_human 5.35x36 185 TM5 Q => A 1.096↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 322 ICL3 S => A N/A N/A Lameh J et al (1992)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 6.38x38 368 TM6 S => A 1.055↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 2.344↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.047↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1999)
acm1_human 4.66x66 166 TM4 Y => A 1.38↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 228 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 2.344↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.122↑ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 15.136↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.0 K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 395 ECL3 V => A 3.548↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.698↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.862↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.778↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.2↓ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.3↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 5.623↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 23.529↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 170 ECL2 E => K 1.148↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.585↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.202↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.49x49 414 TM7 N => H N/A N/A Ballesteros JA et al (2001)
acm1_human 183 ECL2 L => A 5.37↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.26x26 356 TM6 S => A N/A N/A Lameh J et al (1992)
acm1_human 6.58x58 388 TM6 S => Y 111.111↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 6.31↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.111↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.549↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.0↓ K(h) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.175↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.202↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 171 ECL2 R => A 1.23↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1999)
acm1_human 45.51x51 179 ECL2 Y => W 1.072↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.318↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 2.1↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 7.33x32 398 TM7 T => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1998)
acm1_human 6.44x44 374 TM6 F => H N/A N/A Ballesteros JA et al (2001)
acm1_human 3.29x29 102 TM3 L => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 37.154↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.511↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.148↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.318↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 10.965↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.096↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 7.33x32 398 TM7 T => A 1.175↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.549↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 2.291↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.3↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.621↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1993)
acm1_human 6.60x60 390 TM6 F => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 31.623↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2013) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 2.239↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 3.162↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.025↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 22.387↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.318↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.739↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 227.273↓ K(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Thal DM et al (2016) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.75↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 395 ECL3 V => A 436.516↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.7↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 25.704↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 1.548↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.072↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 3.236↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 29.412↑ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 5.62x62 212 TM5 Y => A N/A N/A Hogger P et al (1995)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.66↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 8.53x53 428 H8 T => A N/A N/A Lameh J et al (1992)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 173 ECL2 V => M N/A N/A Lucas JL et al (2001)
acm1_human 2.64x63 85 TM2 Y => A 23.988↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A N/A N/A Matsui H et al (1995)
acm1_human 45.52x52 180 ECL2 I => A 3.311↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 86.275↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 105.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => N N/A N/A Moro O et al (1994)
acm1_human 7.35x34 400 TM7 W => A 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.1↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.862↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 50.119↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Hogger P et al (1995)
acm1_human 45.52x52 180 ECL2 I => A 8.71↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 6.316↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.202↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.862↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 4.8↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 16.596↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 3.472↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F N/A N/A Matsui H et al (1995)
acm1_human 7.35x34 400 TM7 W => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 3.106↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 2.755↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F N/A N/A Drubbisch V et al (1992)
acm1_human 2.56x551 77 TM2 F => I 1.514↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.344↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.621↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 162.181↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 330 ICL3 T => A 1.018↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.259↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.913↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1994)
acm1_human 6.60x60 390 TM6 F => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.692↓ K(i) (Binding - Radioligand competition/displacement) AF-DX 116 Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A N/A N/A Matsui H et al (1995)
acm1_human 7.39x38 404 TM7 Y => F 1.072↑ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 4.8↓ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 5.888↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.479↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 5.37↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 7.244↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.089↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.26x26 356 TM6 S => A 1.091↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.905↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Gregory KJ et al (2010)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Matsui H et al (1995)
acm1_human 6.48x48 378 TM6 W => A 115.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.259↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => F N/A N/A Moro O et al (1994)
acm1_human 7.39x38 404 TM7 Y => A 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.479↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A N/A N/A Hogger P et al (1995)
acm1_human 2.56x551 77 TM2 F => I 4.074↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 55.556↑ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 3.548↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 4.337↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 2.399↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.943↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.349↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 6.897↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 14.791↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 15.556↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F N/A N/A Matsui H et al (1995)
acm1_human 7.39x38 404 TM7 Y => A 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.835↑ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 5.623↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.148↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Hogger P et al (1995)
acm1_human 182 ECL2 F => A 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 4.367↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 322 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.464↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 5.455↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 170 ECL2 E => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.548↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A N/A N/A Matsui H et al (1995)
acm1_human 182 ECL2 F => A 1.202↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Shockley MS et al (1997)
acm1_human 392 ECL3 K => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.062↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.128↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.53x53 133 ICL2 Y => A N/A N/A Moro O et al (1993)
acm1_human 254 ICL3 T => A 2.63↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2008) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.852↓ K(l) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 10.0↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 14.085↑ K(h) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A 10.989↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.35↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Thal DM et al (2016) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 19.953↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 9.772↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 8.128↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.381↑ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 269 ICL3 L => H N/A N/A Ballesteros JA et al (2001)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 870.964↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.38↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 170 ECL2 E => K 14.454↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 394 ECL3 C => A N/A N/A Matsui H et al (1995)
acm1_human 392 ECL3 K => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 2.457↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.25↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F N/A N/A Matsui H et al (1995)
acm1_human 3.28x28 101 TM3 W => F 2.188↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.096↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 2.041↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.311↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.318↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 50.0↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 55.556↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.781↓ K(i) (Binding - Radioligand competition/displacement) APE Huang XP et al (1999) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.259↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.658↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 35.481↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2010) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 56.234↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2013) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 13.183↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.096↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 34.674↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.698↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 5.62x62 212 TM5 Y => A N/A N/A Hogger P et al (1995)
acm1_human 6.52x52 382 TM6 N => A 85.882↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.02↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 1.318↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 24.547↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.291↓ pK(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 184 ECL2 S => A N/A N/A Matsui H et al (1995)
acm1_human 6.52x52 382 TM6 N => A 9.688↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.162↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 13.804↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 27.778↑ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 11.749↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.457↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.088↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.951↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.072↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 272 ICL3 Y => H N/A N/A Ballesteros JA et al (2001)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Leach K et al (2011)
acm1_human 7.32x31 397 TM7 E => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.096↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A 1.758↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.286↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.188↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.53x53 133 ICL2 Y => A N/A N/A Moro O et al (1994)
acm1_human 6.48x48 378 TM6 W => A 1.6↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A N/A N/A Matsui H et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 1.846↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) CDD-0102 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 2.041↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.6↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A 4.848↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Shockley MS et al (1997)
acm1_human 3.37x37 110 TM3 N => A 6.4↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.35↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.096↑ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 13.3↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.869↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.148↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.111↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 181 ECL2 Q => A N/A N/A Matsui H et al (1995)
acm1_human 2.64x63 85 TM2 Y => F 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 3.548↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.259↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.996↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 174 ECL2 L => P 12.589↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.457↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 7.4↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.631↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 2.138↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 18.621↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 5.623↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 6.52x52 382 TM6 N => A 8.182↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 174 ECL2 L => P 1.175↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Shockley MS et al (1997)
acm1_human 6.52x52 382 TM6 N => A 2272.727↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1998)
acm1_human 3.21x21 94 TM3 G => A 2.63↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A N/A N/A Matsui H et al (1995)
acm1_human 4.69x69 169 TM4 G => A 2.399↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 9.0↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.047↑ IC50 (Binding - Radioligand competition/displacement) Atropine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.899↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 288.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.66x66 216 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 90.909↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 3.6↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A N/A N/A Matsui H et al (1995)
acm1_human 2.61x60 82 TM2 Y => A 2.951↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 16.129↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 1.318↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 395 ECL3 V => A 1.35↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => A 3.388↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 177 ECL2 Q => E 1.289↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A N/A N/A Huang XP et al (1999)
acm1_human 5.39x40 189 TM5 T => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A N/A N/A Matsui H et al (1995)
acm1_human 3.32x32 105 TM3 D => E 3.086↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => Y N/A N/A Huang XP et al (1998)
acm1_human 3.28x28 101 TM3 W => F 2.2↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 77.625↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) 4-DAMP Huang XP et al (1999) Vass M et al (2018)
acm1_human 183 ECL2 L => A 11.22↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.939↓ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 171 ECL2 R => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 8.3↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 34.51x51 131 ICL2 L => N N/A N/A Moro O et al (1993)
acm1_human 2.61x60 82 TM2 Y => F 1.575↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 6.0↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 263 ICL3 C => A 2.089↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2008) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 96.7↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 3.02↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Shockley MS et al (1997)
acm1_human 6.24x24 354 TM6 T => A 1.127↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.35↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 2.344↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.047↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.071↓ IC50 (Binding - Radioligand competition/displacement) Atropine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.318↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 1.445↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 3.21x21 94 TM3 G => A 1.381↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.034↓ K(i) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.047↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 2.088↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A N/A N/A Matsui H et al (1995)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 2.951↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 34.56x56 136 ICL2 K => A N/A N/A Moro O et al (1994)
acm1_human 45.51x51 179 ECL2 Y => F 1.072↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↑ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A 2.747↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.762↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >57.692↓ K(i) (Binding - Radioligand competition/displacement) AF-DX 116 Huang XP et al (1999) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 2.512↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 1.818↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.288↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A 1.179↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 2.57↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 7.413↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.949↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 3.546↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.548↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A N/A N/A Matsui H et al (1995)
acm1_human 6.59x59 389 TM6 T => P 3.1↓ K(i) (Binding - Radioligand competition/displacement) Choline Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.024↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 19.1↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1994)
acm1_human 181 ECL2 Q => A 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.386↓ K(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.862↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.862↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 2.95↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 34.6↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A N/A N/A Matsui H et al (1995)
acm1_human 3.28x28 101 TM3 W => F 1.667↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1999)
acm1_human 45.51x51 179 ECL2 Y => A 8.13↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 7.752↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.096↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 172 ECL2 T => A N/A N/A Matsui H et al (1995)
acm1_human 7.39x38 404 TM7 Y => F 6.166↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.25↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A N/A N/A Matsui H et al (1995)
acm1_human 171 ECL2 R => A 4.169↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.02↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 47.863↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2010) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 18.197↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.65x65 215 TM5 T => A N/A N/A Lameh J et al (1992)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 184 ECL2 S => A 1.024↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.166↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 17.378↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 772.727↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 44.668↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 1.259↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.311↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.202↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.137↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.096↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A N/A N/A Matsui H et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 52.308↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 53.703↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Hogger P et al (1995)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 5.62x62 212 TM5 Y => A 1.455↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1993)
acm1_human 45.52x52 180 ECL2 I => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 154.882↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.202↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.524↑ K(i) (Binding - Radioligand competition/displacement) APE Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 58.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.0 pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.318↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 4.365↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 9.772↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.67x67 167 TM4 L => F 1.95↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 5.623↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.52x52 125 TM3 F => A N/A N/A Moro O et al (1993)
acm1_human 23.49x49 90 ECL1 H => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.67x67 167 TM4 L => F 1.024↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 4.898↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 9.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2.545↓ K(h) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 10.0↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 7.762↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 28.84↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.8↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2.788↓ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 43.652↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 7.407↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 13.804↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 11.749↓ pK(i) (Binding - Radioligand competition/displacement) McN-A343 Suga H et al (2013) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 183 ECL2 L => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.51x51 416 TM7 M => A N/A N/A Schlador ML et al (2000)
acm1_human 2.61x60 82 TM2 Y => A 4.074↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 2.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 3.09↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.429↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 3.0↓ K(i) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 20.0↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.148↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.23↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 16.949↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.259↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 19.231↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 24.39↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.412↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.862↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.23↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Hogger P et al (1995)
acm1_human 45.51x51 179 ECL2 Y => A 97.724↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 7.2↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 58.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A N/A N/A Huang XP et al (1999)
acm1_human 6.52x52 382 TM6 N => A 10.87↑ K(i) (Binding - Radioligand competition/displacement) CDD-0034 Huang XP et al (1999) Vass M et al (2018)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 182 ECL2 F => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.349↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1994)
acm1_human 6.59x59 389 TM6 T => P 11.482↓ pK(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 45.709↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 1.259↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.4↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 36.308↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A N/A N/A Hogger P et al (1995)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1993)
acm1_human 7.39x38 404 TM7 Y => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.289↑ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => M N/A N/A Moro O et al (1994)
acm1_human 5.42x43 192 TM5 T => A 3.333↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.021↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 177 ECL2 Q => E 1.38↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.175↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.373↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.621↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 4.785↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.38x38 368 TM6 S => A N/A N/A Lameh J et al (1992)
acm1_human 6.29x29 359 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 3.28x28 101 TM3 W => A 3.236↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A N/A N/A Matsui H et al (1995)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 11000.0↓ K(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 32.258↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 5.129↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 5.0↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.25↑ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.072↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.318↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 1.15↓ K(i) (Binding - Radioligand competition/displacement) Choline Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 6.607↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 5.012↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 2.042↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 3.855↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 171 ECL2 R => A N/A N/A Matsui H et al (1995)
acm1_human 3.32x32 105 TM3 D => E 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1993)
acm1_human 330 ICL3 T => A N/A N/A Lameh J et al (1992)
acm1_human 394 ECL3 C => A 1.514↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1993)
acm1_human 3.37x37 110 TM3 N => Q 1.698↓ pK(i) (Binding - Radioligand competition/displacement) Tiotropium Thal DM et al (2016) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.43x43 116 TM3 L => H N/A N/A Ballesteros JA et al (2001)
acm1_human 6.58x58 388 TM6 S => Y 1.549↓ pK(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.56x56 136 ICL2 K => A N/A N/A Moro O et al (1993)
acm1_human 183 ECL2 L => A 1.66↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 13.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.003↑ K(i) (Binding - Radioligand competition/displacement) CDD-0078 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.479↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 9.7↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.111↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 23.988↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 4.545↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.122↑ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 76.923↑ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.2↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Thal DM et al (2016) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.651↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 10.4↓ K(i) (Binding - Radioligand competition/displacement)