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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
acm1_human 3.28x28 101 TM3 W => A 1.949↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.862↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 3.631↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 13.804↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 4.074↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 5.128↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.943↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.4↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Shockley MS et al (1997)
acm1_human 6.48x48 378 TM6 W => A 34.6↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.318↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.062↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Matsui H et al (1995)
acm1_human 3.49x49 122 TM3 D => N N/A N/A Moro O et al (1994)
acm1_human 182 ECL2 F => A 1.148↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.318↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.072↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.291↓ pK(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1999)
acm1_human 6.51x51 381 TM6 Y => A 34.674↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 5.35x36 185 TM5 Q => A 1.096↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.6↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 7.762↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 12.195↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 2.344↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.52x52 417 TM7 C => S N/A N/A Lucas JL et al (2001)
acm1_human 5.42x43 192 TM5 T => A 1.835↑ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Gregory KJ et al (2010)
acm1_human 2.56x551 77 TM2 F => I 1.862↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 3.02↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.318↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.175↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 2.457↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 42.308↓ K(i) (Binding - Radioligand competition/displacement) p-F-HHSiD Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 128.825↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 5.495↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 322 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.096↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.259↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 2.57↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.815↓ K(i) (Binding - Radioligand competition/displacement) CDD-0078 Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.464↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.202↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 29.412↑ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 4.274↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.35↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.318↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 1.548↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.373↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 3.631↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F N/A N/A Matsui H et al (1995)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 182 ECL2 F => A 3.162↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 7.246↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1994)
acm1_human 45.52x52 180 ECL2 I => A 4.367↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 2.512↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.003↑ K(i) (Binding - Radioligand competition/displacement) CDD-0078 Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.202↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 32.258↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.24x24 354 TM6 T => A N/A N/A Lameh J et al (1992)
acm1_human 7.36x35 401 TM7 E => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.318↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 4.337↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↑ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 115.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.43x43 116 TM3 L => H N/A N/A Ballesteros JA et al (2001)
acm1_human 3.28x28 101 TM3 W => A 23.988↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 58.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 50.0↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A 1.758↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 131.9↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.548↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A N/A N/A Matsui H et al (1995)
acm1_human 23.50x50 91 ECL1 W => A N/A N/A Matsui H et al (1995)
acm1_human 6.51x51 381 TM6 Y => A 2.089↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F N/A N/A Drubbisch V et al (1992)
acm1_human 3.21x21 94 TM3 G => A 2.291↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.62x62 212 TM5 Y => A 1.455↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 9.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.111↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 11.111↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1993)
acm1_human 3.33x33 106 TM3 Y => A 34.674↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.762↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.024↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 45.709↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 4.8↓ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.913↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.148↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 1.318↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.67x67 167 TM4 L => F 1.024↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.429↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 173 ECL2 V => M N/A N/A Lucas JL et al (2001)
acm1_human 170 ECL2 E => K 14.454↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A N/A N/A Hogger P et al (1995)
acm1_human 3.37x37 110 TM3 N => Q 1.35↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Thal DM et al (2016) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A N/A N/A Hogger P et al (1995)
acm1_human 3.33x33 106 TM3 Y => F 1.3↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 55.556↑ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N 1.655↑ Single-point (Binding - Radioligand saturation) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.26x26 356 TM6 S => A 1.091↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 8.71↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A N/A N/A Hogger P et al (1995)
acm1_human 3.28x28 101 TM3 W => A 13.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.722↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 31.623↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2013) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) 4-DAMP Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.778↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.344↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 16.129↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A N/A N/A Matsui H et al (1995)
acm1_human 45.51x51 179 ECL2 Y => F 1.259↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 4.785↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 50.119↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A 10.989↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 5.012↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 2.63↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.862↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 4.677↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 3.546↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 24.39↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1993)
acm1_human 6.52x52 382 TM6 N => A N/A N/A Huang XP et al (1999)
acm1_human 4.64x64 164 TM4 W => A 5.495↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 1.549↓ pK(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) CDD-0102 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.632↑ pK(A) (Binding - Radioligand competition/displacement) 77-LH-28-1 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.166↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 53.703↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 9.12↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => A 3.388↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 15.556↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1993)
acm1_human 34.51x51 131 ICL2 L => M N/A N/A Moro O et al (1993)
acm1_human 4.69x69 169 TM4 G => A 6.31↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F N/A N/A Matsui H et al (1995)
acm1_human 6.52x52 382 TM6 N => A 23.529↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1994)
acm1_human 45.51x51 179 ECL2 Y => A 3.236↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.02↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Shockley MS et al (1997)
acm1_human 7.32x31 397 TM7 E => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.455↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 7.752↑ K(h) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 3.981↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.889↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 6.166↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 9.7↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.23↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 170 ECL2 E => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 228 ICL3 S => A N/A N/A Lameh J et al (1992)
acm1_human 3.21x21 94 TM3 G => A N/A N/A Matsui H et al (1995)
acm1_human 3.32x32 105 TM3 D => N 56.234↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2013) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 31.7↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.0 K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.289↑ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.175↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.575↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.905↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.175↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.025↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 90.909↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.698↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1998)
acm1_human 2.62x61 83 TM2 T => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A N/A N/A Matsui H et al (1995)
acm1_human 2.61x60 82 TM2 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 36.667↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 28.9↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.286↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.587↑ K(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 5.623↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 10.0↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => Y N/A N/A Huang XP et al (1998)
acm1_human 5.42x43 192 TM5 T => A 3.59↓ K(i) (Binding - Radioligand competition/displacement) CDD-0034 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 44.668↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 16.596↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 6.52x52 382 TM6 N => A 85.882↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.047↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.023↓ pK(i) (Binding - Radioligand competition/displacement) QNB Thal DM et al (2016) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 12.303↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.0 pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A N/A N/A Matsui H et al (1995)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.631↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.447↑ K(h) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 170 ECL2 E => K 1.148↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 10.87↑ K(i) (Binding - Radioligand competition/displacement) CDD-0034 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 5.623↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 3.0↓ IC50 (Binding - Radioligand competition/displacement) Pirenzepine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 3.472↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.869↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.128↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => F N/A N/A Moro O et al (1993)
acm1_human 228 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 5.0↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.2↓ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 11.749↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.122↑ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A N/A N/A Matsui H et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 19.231↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 170 ECL2 E => A 1.862↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 2.561↓ IC50 (Binding - Radioligand competition/displacement) Pirenzepine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 8.128↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.862↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.349↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 183 ECL2 L => A 5.37↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.188↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 1.445↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 5.37↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 10.233↓ pK(i) (Binding - Radioligand competition/displacement) McN-A343 Suga H et al (2010) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.781↓ K(i) (Binding - Radioligand competition/displacement) APE Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 3.106↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.862↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 870.964↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 4.571↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 20.0↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 24.547↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Shockley MS et al (1997)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1994)
acm1_human 3.28x28 101 TM3 W => F 2.2↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 252 ICL3 P => A 2.188↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2008) Vass M et al (2018)
acm1_human 3.52x52 125 TM3 F => A N/A N/A Moro O et al (1993)
acm1_human 177 ECL2 Q => E 1.38↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.412↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Thal DM et al (2016) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 371.535↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.667↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A N/A N/A Matsui H et al (1995)
acm1_human 6.52x52 382 TM6 N => A 6.316↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 2.399↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 4.8↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.15↓ K(i) (Binding - Radioligand competition/displacement) CDD-0102 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.089↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.021↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.311↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.38x38 368 TM6 S => A N/A N/A Lameh J et al (1992)
acm1_human 3.21x21 94 TM3 G => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.089↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.381↑ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.259↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 330 ICL3 T => A 1.018↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 76.923↑ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 394 ECL3 C => A 3.636↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N No effect IC50 (Binding - Radioligand competition/displacement) Carbachol Lameh J et al (1992) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 105.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.51x51 416 TM7 M => A N/A N/A Schlador ML et al (2000)
acm1_human 2.56x551 77 TM2 F => I 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 61.111↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F N/A N/A Matsui H et al (1995)
acm1_human 322 ICL3 S => A N/A N/A Lameh J et al (1992)
acm1_human 45.52x52 180 ECL2 I => A 7.244↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => A 660.693↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.511↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 7.2↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 58.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A N/A N/A Matsui H et al (1995)
acm1_human 393 ECL3 D => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.3↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A N/A N/A Matsui H et al (1995)
acm1_human 394 ECL3 C => A 2.137↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 1.6↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.23↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.259↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 2.61x60 82 TM2 Y => A 18.621↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 22.387↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 330 ICL3 T => A N/A N/A Lameh J et al (1992)
acm1_human 6.52x52 382 TM6 N => A >57.692↓ K(i) (Binding - Radioligand competition/displacement) AF-DX 116 Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 19.1↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.479↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 9.772↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.49x49 414 TM7 N => H N/A N/A Ballesteros JA et al (2001)
acm1_human 2.61x60 82 TM2 Y => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.66x66 166 TM4 Y => A 2.455↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.514↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Hogger P et al (1995)
acm1_human 7.35x34 400 TM7 W => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.62x62 212 TM5 Y => A N/A N/A Hogger P et al (1995)
acm1_human 5.65x65 215 TM5 T => A N/A N/A Lameh J et al (1992)
acm1_human 3.29x29 102 TM3 L => A 8.511↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.175↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A N/A N/A Hogger P et al (1995)
acm1_human 6.51x51 381 TM6 Y => A 2.882↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.148↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.8↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 16.218↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 2.512↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F N/A N/A Matsui H et al (1995)
acm1_human 34.51x51 131 ICL2 L => N N/A N/A Moro O et al (1994)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 172 ECL2 T => A N/A N/A Matsui H et al (1995)
acm1_human 34.51x51 131 ICL2 L => F N/A N/A Moro O et al (1994)
acm1_human 6.59x59 389 TM6 T => P 1.939↓ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.514↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.445↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 7.31x30 396 TM7 P => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 3.981↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 28.84↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.95↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.096↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.175↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.621↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 3.333↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 5.455↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 38.019↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 1.259↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 117.49↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.38↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 7.413↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.739↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.441↑ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 171 ECL2 R => A 9.333↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.23↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.02↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 5.129↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 3.6↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.35↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 4.898↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 2.344↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.024↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.096↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.188↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1998)
acm1_human 23.50x50 91 ECL1 W => A 1.818↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 77.625↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.0 pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.096↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 8.13↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 47.863↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2010) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.445↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.202↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.259↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 34.56x56 136 ICL2 K => A N/A N/A Moro O et al (1994)
acm1_human 23.50x50 91 ECL1 W => A 37.154↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 171 ECL2 R => A 1.23↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.71x71 221 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 7.52x52 417 TM7 C => R N/A N/A Lucas JL et al (2001)
acm1_human 3.32x32 105 TM3 D => E 3.162↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 5.64x64 214 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 7.31x30 396 TM7 P => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.67x67 167 TM4 L => F 1.95↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.651↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.023↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 263 ICL3 C => A 2.089↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2008) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.096↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.047↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 7.407↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.25↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1994)
acm1_human 45.52x52 180 ECL2 I => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F N/A N/A Drubbisch V et al (1992)
acm1_human 392 ECL3 K => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 86.275↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 272 ICL3 Y => H N/A N/A Ballesteros JA et al (2001)
acm1_human 4.65x65 165 TM4 Q => A N/A N/A Matsui H et al (1995)
acm1_human 4.65x65 165 TM4 Q => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.66x66 216 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 5.35x36 185 TM5 Q => A 1.318↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 4.545↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.585↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.75↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.62x62 212 TM5 Y => A N/A N/A Hogger P et al (1995)
acm1_human 269 ICL3 L => H N/A N/A Ballesteros JA et al (2001)
acm1_human 23.49x49 90 ECL1 H => A 1.047↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.692↓ K(i) (Binding - Radioligand competition/displacement) AF-DX 116 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.951↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.072↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 2.088↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 184 ECL2 S => A N/A N/A Matsui H et al (1995)
acm1_human 5.42x43 192 TM5 T => A 3.0↓ K(i) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 2.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.072↑ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.479↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 1.318↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 2.95↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 2.951↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.202↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.82↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 162.181↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A N/A N/A Matsui H et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 52.308↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 3.236↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 3.548↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.074↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.175↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 13.49↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 2.239↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 5.623↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.698↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 6.44x44 374 TM6 F => A 5.623↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.513↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.56x56 136 ICL2 K => A N/A N/A Moro O et al (1993)
acm1_human 184 ECL2 S => A 1.202↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 2.3↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 25.704↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 13.183↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 7.244↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 6.31↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Shockley MS et al (1997)
acm1_human 6.26x26 356 TM6 S => A N/A N/A Lameh J et al (1992)
acm1_human 3.37x37 110 TM3 N => Q 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Thal DM et al (2016) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 288.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Hogger P et al (1995)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.318↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 177 ECL2 Q => E 1.289↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 97.724↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 3.086↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.479↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 11.22↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.549↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 14.791↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A 2.747↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.549↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 45.51x51 179 ECL2 Y => F 1.35↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.0↓ K(h) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 9.688↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 36.308↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 3.89↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 29.512↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 19.953↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.111↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 18.197↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.072↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1999)
acm1_human 7.35x34 400 TM7 W => F 10.0↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 6.38x38 368 TM6 S => A 1.055↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 6.0↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 43.652↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2.545↓ K(h) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 7.46x46 411 TM7 S => A 1.1↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 2.951↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 6.607↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 26.303↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.174↑ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 5.248↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 17.378↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1993)
acm1_human 6.31x31 361 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) p-F-HHSiD Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 16.982↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.457↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 174 ECL2 L => P 12.589↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 2.138↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.096↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1994)
acm1_human 4.66x66 166 TM4 Y => A 1.38↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 35.481↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2010) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 2.138↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 4.65x65 165 TM4 Q => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.259↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 5.888↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 2.042↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 55.556↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 227.273↓ K(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 171 ECL2 R => A N/A N/A Matsui H et al (1995)
acm1_human 183 ECL2 L => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.122↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.071↓ IC50 (Binding - Radioligand competition/displacement) Atropine Drubbisch V et al (1992) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 3.388↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.7↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 395 ECL3 V => A 1.35↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 3.09↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 7.586↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.088↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 394 ECL3 C => A N/A N/A Matsui H et al (1995)
acm1_human 6.58x58 388 TM6 S => Y 16.949↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 66.1↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2272.727↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 183 ECL2 L => A 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 3.236↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.35↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 13.183↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 27.542↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1999)
acm1_human 6.59x59 389 TM6 T => P 11.482↓ pK(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.38↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.412↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1994)
acm1_human 3.37x37 110 TM3 N => Q 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Thal DM et al (2016) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 2.041↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 6.918↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.0 pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.548↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.621↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 3.333↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.29x29 359 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 6.51x51 381 TM6 Y => A 2.457↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.202↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 182 ECL2 F => A 2.512↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.349↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.667↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.698↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.53x53 133 ICL2 Y => A N/A N/A Moro O et al (1993)
acm1_human 6.58x58 388 TM6 S => Y 111.111↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.739↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.311↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 13.804↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.455↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 3.236↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 772.727↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 395 ECL3 V => A 3.548↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 76.923↑ pK(A) (Binding - Radioligand competition/displacement) 77-LH-28-1 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 284 ICL3 S => A 1.196↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Moro O et al (1993) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.175↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A 1.179↑ IC50 (Binding - Radioligand competition/displacement) Carbachol