Structure information

CCR7

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6QZH

SPECIES

Homo sapiens

RESOLUTION

2.100

PREFERRED CHAIN

A

PUBLICATION DATE

Sept. 4, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
SCHEMBL13407377 V79 1.53x53 TM1 hydrophobic
SCHEMBL13407377 F86 ICL1 hydrophobic
SCHEMBL13407377 T91 2.37x37 TM2 polar (hydrogen bond)
SCHEMBL13407377 T93 2.39x39 TM2 polar (hydrogen bond)
SCHEMBL13407377 T93 2.39x39 TM2 polar (hydrogen bond)
SCHEMBL13407377 D94 2.40x40 TM2 polar (charge-assisted hydrogen bond)
SCHEMBL13407377 D94 2.40x40 TM2 polar (charge-assisted hydrogen bond)
SCHEMBL13407377 D94 2.40x40 TM2 polar (charge-assisted hydrogen bond)
SCHEMBL13407377 D94 2.40x40 TM2 polar (charge-assisted hydrogen bond)
SCHEMBL13407377 L97 2.43x43 TM2 hydrophobic
SCHEMBL13407377 I262 ICL3 hydrophobic
SCHEMBL13407377 Y326 7.53x53 TM7 polar (hydrogen bond with backbone)
SCHEMBL13407377 V331 ICL4 polar (hydrogen bond with backbone)
SCHEMBL13407377 K332 8.49x49 H8 polar (hydrogen bond with backbone)
SCHEMBL13407377 F333 8.50x50 H8 polar (hydrogen bond with backbone)

Ligands

SCHEMBL13407377

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Residue Diagrams

G N G L L G V F C I I S Y M I P L F W A 1 L N L A V A D I L F L L T L P F W A Y S 2 C L L L L M G S F F S M K Y I A F I L K 3 S K L S C V G I W I L A T V L S I P E 4 Y C F S M A L L P V L F G I V M Q A V Q I 5 I A V V V V F I V F Q L P Y N G V V L A 6 F P N V C C R V C A L S Y T V D Y A I 7
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ICL1 K R L K ICL1ECL1 S W V F ECL1ICL2 A V S A H R H R A R ICL2ECL2 D L Q R S S S E Q A M R C S L I T E H V ECL2ICL3 R N ICL3ECL3 T S S ECL3N-term M D L G K P M K S V L V V A L L V I F Q V C L C Q D E V T D D Y I G D N T T V D Y T L F E S L C S K K D V R N-termC-term D L G C L S Q E Q L R Q W S S C R H I R R S S M S V E A E T T T T F S P C-term N F K A W F L P I M Y S I I C F V G L L G N G L V V L T Y I Y F T M T D T Y L L N L A V A D I L F L L T L P F W A Y S A A K G V H F C K L I F A I Y K M S F F S G M L L L L C I S I D R Y V A I V Q V L L I S K L S C V G I W I L A T V L S I P E L L Y S E A F I T I Q V A Q M V I G F L V P L L A M S F C Y L V I I R T L L Q A F E R N K A I K V I I A V V V V F I V F Q L P Y N G V V L A Q T V A N F N I T C E L S K Q L N I A Y D V T Y S L A C V R C C V N P F L Y A F I G V K L F K F R N D L F K
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Residue Table


GPCRdb(A)
GPCRdb(A)
CCR7
TM1
1x53 1.53x53 V79
TM2
2x37 2.37x37 T91
2x39 2.39x39 T93
2x40 2.40x40 D94
2x43 2.43x43 L97
TM7
7x53 7.53x53 Y326
H8
8x49 8.49x49 K332
8x50 8.50x50 F333