Structure information

C5a1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5O9H

SPECIES

Homo sapiens

RESOLUTION

2.700

PREFERRED CHAIN

A

REFERENCE

10.1038/NATURE25025

PUBLICATION DATE

Jan. 10, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
NDT9513727 I124 3.40x40 TM3 hydrophobic
NDT9513727 L125 3.41x41 TM3 hydrophobic
NDT9513727 A128 3.44x44 TM3 hydrophobic
NDT9513727 L156 4.45x45 TM4 hydrophobic
NDT9513727 V159 4.48x48 TM4 hydrophobic
NDT9513727 L163 4.52x52 TM4 hydrophobic
NDT9513727 L209 5.45x46 TM5 hydrophobic
NDT9513727 W213 5.49x49 TM5 Van der Waals
NDT9513727 W213 5.49x49 TM5 polar (hydrogen bond)
NDT9513727 P214 5.50x50 TM5 hydrophobic
NDT9513727 P214 5.50x50 TM5 Van der Waals
NDT9513727 T217 5.53x53 TM5 Van der Waals

Ligands

NDT9513727

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Residue Diagrams

A N G L V G V L F V V A F I V L A L I D 1 L N L A V A D F L S C L A L P I L F T S 2 T A L L L I S A Y M N L L I L S P L I S 3 A W I A C A V A W G L A L L L T I P S 4 Y C I T L T L L P W L F G L V L R V I A V 5 V A V V A S F F I F W L P Y Q V T G I M 6 I P N I C C N I Y A F S V C L S D L K 7
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ICL1 A K R ICL1ECL1 H H W P F ECL1ICL2 P I W C Q N F R ICL2ECL2 V V R E E Y F P P K V L C G V D Y S H ECL2ICL3 R A T R S ICL3ECL3 E P S ECL3N-term M D S F N Y T T P D Y G H Y D D K D T L D L N T P V D K T S N T L N-termC-term Q G F Q G R L R K S L P S L L R N V L T E E S V V R E S K S F T R S T V D T M A Q K T Q A V C-term R V P D I L A L V I F A V V F L V G V L G N A L V V W V T A F E T I N A I W F L N L A V A D F L S C L A L P I L F T S I V Q H G G A A C S I L P S L I L L N M Y A S I L L L A T I S A D R F L L V F K G A G L A W I A C A V A W G L A L L L T I P S F L Y R D K R R E R A V A I V R L V L G F L W P L L T L T I C Y T F I L L R T W S R T K T L K V V V A V V A S F F I F W L P Y Q V T G I M M S F L S P T F L L L K K L D S L C V S F A Y I N C C I N P I I Y V V A G
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Residue Table


GPCRdb(A)
GPCRdb(A)
C5a1 receptor
TM3
3x40 3.40x40 I124
3x41 3.41x41 L125
3x44 3.44x44 A128
TM4
4x45 4.45x45 A156
4x48 4.48x48 V159
4x52 4.52x52 L163
TM5
5x46 5.45x46 L209
5x49 5.49x49 W213
5x50 5.50x50 P214
5x53 5.53x53 T217