Structure information

5-HT1B receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4IAQ

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

REFERENCE

10.1126/SCIENCE.1232807

PUBLICATION DATE

March 13, 2013

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Dihydroergotamine D129 3.32x32 TM3 polar (charge-charge)
Dihydroergotamine I130 3.33x33 TM3 hydrophobic
Dihydroergotamine C133 3.36x36 TM3 hydrophobic
Dihydroergotamine T134 3.37x37 TM3 polar (hydrogen bond)
Dihydroergotamine V200 45.51x51 ECL2 hydrophobic
Dihydroergotamine V201 45.52x52 ECL2 polar (hydrogen bond with backbone)
Dihydroergotamine A216 5.46x461 TM5 hydrophobic
Dihydroergotamine F330 6.51x51 TM6 hydrophobic
Dihydroergotamine F331 6.52x52 TM6 aromatic (edge-to-face)
Dihydroergotamine M337 6.58x58 TM6 hydrophobic
Dihydroergotamine F351 7.35x34 TM7 hydrophobic

Ligands

Dihydroergotamine

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

A N S L T T A L T I L A L L M V L L V K 1 A S L A V T D L L V S L I V M P I S T M Y 2 V C L H L I S A T C C T I D S S L W F D 3 A A V M I A L V W V F S I S I S L P P F 4 Y L A I L L L T P F Y F A G V T S Y V T Y 5 G I I L G A F I V C W L P F F I I S L V 6 I P N I L S N L Y G L W T F F D F I A 7
Download: PNG | SVG
ICL1 R K L H ICL1ECL1 R W T L ECL1ICL2 A V E Y S A K R ICL2ECL2 R Q A K A E E E V S E C V V N T D ECL2ICL3 N R T G K R L T R A Q L I T D S P G S T S S V T S I N S R V P D V P S E S G S P V Y V N Q V K V R V S D A L L E K K ICL3ECL3 C K D A C W F ECL3N-term M E E P G A Q C A P P P P A G S E T W V P Q A N L S S A P S Q N C S A K D Y I Y Q D S I N-termC-term R F K C T S C-term S L P W K V L L V M L L A L I T L A T T L S N A F V I A T V Y R T T P A N Y L I A S L A V T D L L V S I L V M P I S T M Y T V T G G Q V V C D F W L S S D I T C C T A S I L H L C V I A L D R Y W A I T D T P K R A A V M I A L V W V F S I S I S L P P F F W H I L Y T V Y S T V G A F Y F P T L L L I A L Y G R I Y V E A R S R I L K Q T P K L M A A R E R K A T K T L G I I L G A F I V C W L P F F I I S L V M P I H L A I F D F F T W L G Y L N S L I N P I I Y T M S N E D F H K F K Q A L I
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
5-HT1B receptor
TM3
3x32 3.32x32 D129
3x33 3.33x33 I130
3x36 3.36x36 C133
3x37 3.37x37 T134
ECL2
45x51 45.51x51 V200
45x52 45.52x52 V201
TM5
5x461 5.46x461 A216
TM6
6x51 6.51x51 F330
6x52 6.52x52 F331
6x58 6.58x58 M337
TM7
7x34 7.35x34 F351